A case report of breakthrough infection with the SARS-CoV-2 delta variant and household transmission: Role of vaccination, anti-spike IgG and neutralizing activity.

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作者： Yuki,Moriyama ^[1] ; Masahiro,Ishikane ^[2] ; Mikako,Ueno ^[3] ; Akihiro,Matsunaga ^[3] ; Yukihito,Ishizaka ^[3] ; Takeshi,Arashiro ^[4] ; Takayuki,Kanno ^[5] ; Tadaki,Suzuki ^[5] ; Kenjiro,Kimura ^[6]

作者单位： Department of Infectious Disease, Tokyo Takanawa Hospital, 3-10-11 Takanawa, Minato, Tokyo, 108-8606, Japan; Collaborative Chairs Emerging and Reemerging Infectious Diseases, National Center for Global Health and Medicine, Graduate School of Medicine, Tohoku University, 41 Kawauchi, Aoba-ku, Sendai, 980-0872, Japan. Electronic address: moriyama-yuki@takanawa.jcho.go.jp. ^[1] Disease Control and Prevention Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan. ^[2] Department of Intractable Diseases, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan. ^[3] Department of Pathology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan; Center for Surveillance, Immunization, and Epidemiologic Research, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan. ^[4] Department of Pathology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8640, Japan. ^[5] Tokyo Takanawa Hospital, 3-10-11 Takanawa, Minato, Tokyo, 108-8606, Japan. ^[6]

关键词 Anti-spike IgG BNT162b2 vaccine Breakthrough infection Delta variant Neutralizing antibodies SARS-CoV-2 infection

主题词成年人(Adult);抗体, 中和(Antibodies, Neutralizing);抗体, 病毒(Antibodies, Viral);女(雌)性(Female);人类(Humans);免疫球蛋白G(Immunoglobulin G);接种(Vaccination)

DOI 10.1016/j.jiac.2022.02.003

PMID 35461768

发布时间 2022-07-16

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