Weight-bearing activity impairs nuclear membrane and genome integrity via YAP activation in plantar melanoma.

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第一作者： Jimyung,Seo

第一单位： Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.

作者： Jimyung,Seo ^[1] ; HyunSeok,Kim ^[1] ; Kyoung Il,Min ^[1] ; Changgon,Kim ^[1] ; Yongsoo,Kwon ^[1] ; Zhenlong,Zheng ^[2] ; Yusung,Kim ^[3] ; Hyung-Soon,Park ^[3] ; Young Seok,Ju ^[1] ; Mi Ryung,Roh ^[4] ; Kee Yang,Chung ^[5] ; Joon,Kim ^[6]

作者单位： Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea. ^[1] Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. ^[2] Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea. ^[3] Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. karenroh@yuhs.ac. ^[4] Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea. kychung@yuhs.ac. ^[5] Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea. joonkim@kaist.ac.kr. ^[6]

主题词人类(Humans);黑色素瘤(Melanoma);核被膜(Nuclear Envelope);皮肤肿瘤(Skin Neoplasms);负重(Weight-Bearing)

DOI 10.1038/s41467-022-29925-x

PMID 35468978

发布时间 2023-12-13

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