Somatic whole genome dynamics of precancer in Barrett's esophagus reveals features associated with disease progression.

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第一作者： Thomas G,Paulson

第一单位： Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA. tpaulson@fredhutch.org.

作者： Thomas G,Paulson ^[1] ; Patricia C,Galipeau ^[2] ; Kenji M,Oman ^[2] ; Carissa A,Sanchez ^[2] ; Mary K,Kuhner ^[3] ; Lucian P,Smith ^[4] ; Kevin,Hadi ^[3] ; Minita,Shah ^[5] ; Kanika,Arora ^[5] ; Jennifer,Shelton ^[5] ; Molly,Johnson ^[5] ; Andre,Corvelo ^[5] ; Carlo C,Maley ^[5] ; Xiaotong,Yao ^[6] ; Rashesh,Sanghvi ^[5] ; Elisa,Venturini ^[5] ; Anne-Katrin,Emde ^[5] ; Benjamin,Hubert ^[7] ; Marcin,Imielinski ^[5] ; Nicolas,Robine ^[5] ; Brian J,Reid ^[8] ; Xiaohong,Li ^[5]

作者单位： Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA. tpaulson@fredhutch.org. ^[1] Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA. ^[2] Department of Genome Sciences, University of Washington, Seattle, WA, 98195-5065, USA. ^[3] Brotman Baty Institute for Precision Medicine, Seattle, WA, 98195-5065, USA. ^[4] New York Genome Center (NYGC), New York, NY, 10013, USA. ^[5] Arizona Cancer Evolution Center, Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, AZ, 85281, USA. ^[6] Variant Bio, Brooklyn, NY, 11205, USA. ^[7] Department of Pathology and Laboratory Medicine, Englander Institute for Precision Medicine, Institute for Computational Biomedicine and Meyer Cancer Center, Weill Cornell Medical College, New York, NY, 10065, USA. ^[8] Department of Medicine, University of Washington, Seattle, WA, 98195, USA. ^[9] Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109-1024, USA. xili@fredhutch.org. ^[10]

主题词腺癌(Adenocarcinoma);Barrett食管(Barrett Esophagus);疾病恶化(Disease Progression);食管肿瘤(Esophageal Neoplasms);人类(Humans)

DOI 10.1038/s41467-022-29767-7

PMID 35484108

发布时间 2022-11-12

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