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Individualized pathway activity algorithm identifies oncogenic pathways in pan-cancer analysis.

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第一作者： Xin,Ke

第一单位： Key Laboratory of Biomedical Information Engineering of Ministry of Education, Biomedical Informatics and Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China.

作者： Xin,Ke ^[1] ; Hao,Wu ^[1] ; Yi-Xiao,Chen ^[2] ; Yan,Guo ^[1] ; Shi,Yao ^[2] ; Ming-Rui,Guo ^[1] ; Yuan-Yuan,Duan ^[1] ; Nai-Ning,Wang ^[1] ; Wei,Shi ^[1] ; Chen,Wang ^[1] ; Shan-Shan,Dong ^[1] ; Huafeng,Kang ^[3] ; Zhijun,Dai ^[4] ; Tie-Lin,Yang ^[5]

作者单位： Key Laboratory of Biomedical Information Engineering of Ministry of Education, Biomedical Informatics and Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China. ^[1] National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710004, PR China. ^[2] Department of Oncology, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710004, PR China. ^[3] Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, PR China. ^[4] Key Laboratory of Biomedical Information Engineering of Ministry of Education, Biomedical Informatics and Genomics Center, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, PR China; National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710004, PR China. Electronic address: yangtielin@xjtu.edu.cn. ^[5]

关键词 KEGG pathways Oncogenic pathways Pan-cancer analysis Pathway activity algorithm

医学主题词算法(Algorithms);脂肪酸类(Fatty Acids);基因表达谱(Gene Expression Profiling);人类(Humans);肿瘤(Neoplasms);癌基因(Oncogenes)

DOI 10.1016/j.ebiom.2022.104014

PMID 35487057

发布时间 2022-07-16

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