Novel hepatitis B virus reverse transcriptase mutations in patients with sustained viremia despite long-term tenofovir treatment.

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作者： Anni,Winckelmann ^[1] ; Ulrik,Fahnøe ^[2] ; Priyanka Shukla,Bajpai ^[2] ; Magnus Illum,Dalegaard ^[2] ; Andreas,Lundh ^[3] ; Lene,Ryom ^[4] ; Jens,Bukh ^[2] ; Nina,Weis ^[5]

作者单位： Department of Infectious Diseases, Copenhagen University Hospital - Hvidovre, Copenhagen, Denmark; Copenhagen Hepatitis C Program (CO-HEP), Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: anniw@dadlnet.dk. ^[1] Department of Infectious Diseases, Copenhagen University Hospital - Hvidovre, Copenhagen, Denmark; Copenhagen Hepatitis C Program (CO-HEP), Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ^[2] Department of Infectious Diseases, Copenhagen University Hospital - Hvidovre, Copenhagen, Denmark; Cochrane Denmark & Centre for Evidence-Based Medicine Odense, Department of Clinical Research, University of Southern Denmark, Odense, Denmark. ^[3] Department of Infectious Diseases, Copenhagen University Hospital - Hvidovre, Copenhagen, Denmark; CHIP, Centre of Excellence for Health, Immunity and Infections, section 2100, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. ^[4] Department of Infectious Diseases, Copenhagen University Hospital - Hvidovre, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. ^[5]

关键词 DANHEP Hepatitis B virus infection Hepatitis B virus sequencing Tenofovir disoproxil fumarate Tenofovir resistance