Mosquitocidal efficacy of embelin and its derivatives against Aedes aegypti L. and Culex quinquefasciatus Say. (Diptera: Culicidae) and computational analysis of acetylcholinesterase 1 (AChE1) inhibition.

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作者： Antony,Stalin ^[1] ; Appadurai,Daniel Reegan ^[2] ; Munusamy,Rajiv Gandhi ^[3] ; R R,Saravanan ^[4] ; Kedike,Balakrishna ^[5] ; Abd El-Latif,Hesham ^[6] ; Savarimuthu,Ignacimuthu ^[7] ; Ying,Zhang ^[8]

作者单位： Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu, 610 054, China. Electronic address: a.staanlin@gmail.com. ^[1] National Centre for Disease Control, Bengaluru Branch, No:8, NTI Campus, Bellary Road, Bengaluru, 560 003, Karnataka, India; Xavier Research Foundation, St. Xavier's College, Affiliated to the Manonmaniam Sundaranar University, Palayamkottai, 627 002, Tamil Nadu, India. Electronic address: danielreegan85@gmail.com. ^[2] National Biodiversity Authority, 5th Floor, CSIR Road, TICEL Bio Park, Taramani, Chennai, 600 113, India. ^[3] Department of Physics, Meenakshi Chandrasekaran College of Arts and Science, Karambayam, Pattukkottai, Thanjavur, 614 626, India. ^[4] Entomology Research Institute, Loyola College, Affiliated to the University of Madras, Chennai, 600 034, Tamil Nadu, India. ^[5] Genetics Department, Faculty of Agriculture, Beni-Suef University, Beni-Suef, 62511, Egypt. ^[6] Xavier Research Foundation, St. Xavier's College, Affiliated to the Manonmaniam Sundaranar University, Palayamkottai, 627 002, Tamil Nadu, India. ^[7] Department of Anesthesiology, Hospital (T.C.M) Affiliated To Southwest Medical University, Luzhou, China. Electronic address: zhangying021210@163.com. ^[8]

关键词 Aedes aegypti Culex quinquefasciatus Derivatives Embelin Molecular docking Molecular dynamics Mosquitocidal efficacy

主题词乙酰胆碱酯酶(Acetylcholinesterase);伊蚊属(Aedes);动物(Animals);苯醌类(Benzoquinones);库蚊属(Culex);幼虫(Larva);植物提取物(Plant Extracts)

DOI 10.1016/j.compbiomed.2022.105535

PMID 35487124

发布时间 2022-07-29

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