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首页> Molecular pharmacology> Discovery of Novel Activators of Large-Conductance Calcium-Activated Potassium Channels for the Treatment of Cerebellar Ataxia.

Discovery of Novel Activators of Large-Conductance Calcium-Activated Potassium Channels for the Treatment of Cerebellar Ataxia.

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作者： Sharan R,Srinivasan ^[1] ; Haoran,Huang ^[1] ; Wei-Chih,Chang ^[1] ; Joshua A,Nasburg ^[1] ; Hai M,Nguyen ^[1] ; Tim,Strassmaier ^[1] ; Heike,Wulff ^[1] ; Vikram G,Shakkottai ^[2]

作者单位： Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.). ^[1] Brigham and Women's Hospital, Department of Neurology, Boston, Massachusetts (S.R.S.); University of Texas Southwestern Medical Center, Department of Neurology, Dallas, Texas (H.H., V.G.S.); University of Michigan, Department of Neurology, Ann Arbor, Michigan (S.R.S., W.-C.C.); University of California, Davis, Department of Pharmacology, Davis, California (J.A.N., H.M.N., H.W.); and Nanion Technologies, Munich, Germany (T.S.) Vikram.Shakkottai@UTSouthwestern.edu. ^[2]

主题词动物(Animals);共济失调(Ataxia);钙(Calcium);小脑共济失调(Cerebellar Ataxia);大电导钙激活钾通道(Large-Conductance Calcium-Activated Potassium Channels);小鼠(Mice);钾(Potassium);钾通道, 钙激活(Potassium Channels, Calcium-Activated);脊髓小脑共济失调(Spinocerebellar Ataxias)

DOI 10.1124/molpharm.121.000478

PMID 35489717

发布时间 2025-02-13

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Molecular pharmacology

Molecular pharmacology

2022年102卷1期

438-449页

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