Tumor-infiltrating ICOS<sup>+</sup> Effector Regulatory T-Cells in Oral Squamous Cell Carcinoma as a Promising Biomarker for Prognosis and 'Hot' Tumor.

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第一作者： Hitomi,Kajikawa

第一单位： Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Suita, Japan.

作者： Hitomi,Kajikawa ^[1] ; Michinari,Hirata ^[2] ; Miya,Haruna ^[1] ; Azumi,Ueyama ^[3] ; Katsutoshi,Hirose ^[1] ; Atsunari,Kawashima ^[3] ; Kota,Iwahori ^[1] ; Kazuhide,Matsunaga ^[3] ; Satoru,Toyosawa ^[4] ; Narikazu,Uzawa ^[1] ; Hisashi,Wada ^[5]

作者单位： Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Suita, Japan. ^[1] Department of Oral and Maxillofacial Surgery II, Graduate School of Dentistry, Osaka University, Suita, Japan. ^[2] Drug Discovery & Disease Research Laboratory, Shionogi & Co., Ltd., Toyonaka, Japan. ^[3] Department of Oral Pathology, Graduate School of Dentistry, Osaka University, Suita, Japan. ^[4] Department of Urology, Graduate School of Medicine, Osaka University, Suita, Japan. ^[5] Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Suita, Japan; hwada@gesurg.med.osaka-u.ac.jp. ^[6]

关键词 Oral squamous cell carcinoma flow cytometry immune checkpoint regulatory T-lymphocytes tumor-infiltrating lymphocytes

主题词癌, 鳞状细胞(Carcinoma, Squamous Cell);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);口腔肿瘤(Mouth Neoplasms);预后(Prognosis);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);肿瘤微环境(Tumor Microenvironment)

DOI 10.21873/anticanres.15717

PMID 35489733

发布时间 2022-05-03

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