Depletion of RNASEH2 Activity Leads to Accumulation of DNA Double-strand Breaks and Reduced Cellular Survivability in T Cell Leukemia.

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作者： Dipayan,Ghosh ^[1] ; Susmita,Kumari ^[1] ; Sathees C,Raghavan ^[2]

作者单位： Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India. ^[1] Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India. Electronic address: sathees@iisc.ac.in. ^[2]

关键词 DSB repair Pol mu double-strand break error-prone polymerase pol X family

主题词 DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA修复(DNA Repair);基因敲低技术(Gene Knockdown Techniques);人类(Humans);Jurkat细胞(Jurkat Cells);白血病, T细胞(Leukemia, T-Cell);RNA, 小分子干扰(RNA, Small Interfering);核糖核酸酶H(Ribonuclease H)

DOI 10.1016/j.jmb.2022.167617

PMID 35500843

发布时间 2022-08-07

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Journal of molecular biology

2022年434卷12期

167617页

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Depletion of RNASEH2 Activity Leads to Accumulation of DNA Double-strand Breaks and Reduced Cellular Survivability in T Cell Leukemia.

Journal of molecular biology

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Journal of molecular biology

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Depletion of RNASEH2 Activity Leads to Accumulation of DNA Double-strand Breaks and Reduced Cellular Survivability in T Cell Leukemia.

Journal of molecular biology

相似文献

Journal of molecular biology

相关期刊

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