Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes.

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第一作者： Emilia,Huvinen

第一单位： Teratology Information Service, Department of Emergency Medicine and Services, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. emilia.huvinen@helsinki.fi.

作者： Emilia,Huvinen ^[1] ; Jari,Lahti ^[2] ; Miira M,Klemetti ^[3] ; Paula H,Bergman ^[4] ; Katri,Räikkönen ^[2] ; Marju,Orho-Melander ^[5] ; Hannele,Laivuori ^[6] ; Saila B,Koivusalo ^[7]

作者单位： Teratology Information Service, Department of Emergency Medicine and Services, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. emilia.huvinen@helsinki.fi. ^[1] Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland. ^[2] Department of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. ^[3] Biostatistics Consulting, Department of Public Health, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. ^[4] Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden. ^[5] Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland.;Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.;Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. ^[6] Department of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.;Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland. ^[7]

关键词 Diet Genetic risk Gene–environment interaction Gestational diabetes Lifestyle intervention Physical activity Polygenic risk score Prevention Type 2 diabetes