首页> Oncogene> Insufficient ablation induces E3-ligase Nedd4 to promote hepatocellular carcinoma progression by tuning TGF-β signaling.

Insufficient ablation induces E3-ligase Nedd4 to promote hepatocellular carcinoma progression by tuning TGF-β signaling.

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第一作者： Kai,Li

第一单位： State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, PR China.;Department of Liver Surgery, Sun Yat-sen University Cancer Center, Guangzhou, PR China.

作者： Kai,Li ^[1] ; Yi,Niu ^[2] ; Yichuan,Yuan ^[1] ; Jiliang,Qiu ^[1] ; Yunxing,Shi ^[1] ; Chengrui,Zhong ^[1] ; Zhiyu,Qiu ^[1] ; Keren,Li ^[1] ; Zhu,Lin ^[1] ; Zhenkun,Huang ^[1] ; Chao,Zhang ^[3] ; Dinglan,Zuo ^[2] ; Wei,He ^[1] ; Yunfei,Yuan ^[4] ; Binkui,Li ^[5]

作者单位： State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, PR China.;Department of Liver Surgery, Sun Yat-sen University Cancer Center, Guangzhou, PR China. ^[1] State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, PR China. ^[2] State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, PR China.;Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, PR China. ^[3] State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, PR China. yuanyf@mail.sysu.edu.cn.;Department of Liver Surgery, Sun Yat-sen University Cancer Center, Guangzhou, PR China. yuanyf@mail.sysu.edu.cn. ^[4] State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, PR China. libk@sysucc.org.cn.;Department of Liver Surgery, Sun Yat-sen University Cancer Center, Guangzhou, PR China. libk@sysucc.org.cn. ^[5]

医学主题词癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans);肝肿瘤(Liver Neoplasms);转化生长因子β(Transforming Growth Factor beta);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)

DOI 10.1038/s41388-022-02334-6

PMID 35501461

发布时间 2022-11-14

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准确一般字义偏差语意偏离译文作用小提交