An extended amygdala-midbrain circuit controlling cocaine withdrawal-induced anxiety and reinstatement.

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作者： Guilian,Tian ^[1] ; May,Hui ^[1] ; Desiree,Macchia ^[1] ; Pieter,Derdeyn ^[2] ; Alexandra,Rogers ^[3] ; Elizabeth,Hubbard ^[1] ; Chengfeng,Liu ^[1] ; Jose J,Vasquez ^[1] ; Lara,Taniguchi ^[3] ; Katrina,Bartas ^[2] ; Sean,Carroll ^[1] ; Kevin T,Beier ^[4]

作者单位： Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA 92617, USA. ^[1] Program in Mathematical, Computational, and Systems Biology, University of California, Irvine, Irvine, CA 92617, USA. ^[2] Interdepartmental Neuroscience Program, University of California, Irvine, Irvine, CA 92617, USA. ^[3] Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA 92617, USA; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, CA 92617, USA; Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92617, USA; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92617, USA; Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA 92617, USA; UCI Mind, University of California, Irvine, Irvine, CA 92617, USA. Electronic address: kbeier@uci.edu. ^[4]

关键词 CP: Neuroscience addiction anxiety calcium imaging chemogenetics cocaine withdrawal dopamine extended amygdala rabies circuit mapping reinstatement

主题词杏仁核(Amygdala);焦虑(Anxiety);可卡因(Cocaine);可卡因相关性障碍(Cocaine-Related Disorders);多巴胺(Dopamine);人类(Humans);腹侧被盖区(Ventral Tegmental Area)

DOI 10.1016/j.celrep.2022.110775

PMID 35508124

发布时间 2024-05-15

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