Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.
第一作者:
Aniket,Mishra
第一单位:
University of Bordeaux, INSERM, Bordeaux Population Health Research Centre, Team ELEANOR, UMR 1219, F-33000 Bordeaux, France.
作者:
Aniket,Mishra [1]
;
Cécile,Duplaà [2]
;
Dina,Vojinovic [3]
;
Hideaki,Suzuki [4]
;
Muralidharan,Sargurupremraj [1]
;
Nuno R,Zilhão [5]
;
Shuo,Li [6]
;
Traci M,Bartz [7]
;
Xueqiu,Jian [8]
;
Wei,Zhao [9]
;
Edith,Hofer [10]
;
Katharina,Wittfeld [11]
;
Sarah E,Harris [12]
;
Sandra,van der Auwera-Palitschka [11]
;
Michelle,Luciano [12]
;
Joshua C,Bis [13]
;
Hieab H H,Adams [14]
;
Claudia L,Satizabal [15]
;
Rebecca F,Gottesman [16]
;
Piyush G,Gampawar [17]
;
Robin,Bülow [18]
;
Stefan,Weiss [19]
;
Miao,Yu [9]
;
Mark E,Bastin [20]
;
Oscar L,Lopez [21]
;
Meike W,Vernooij [22]
;
Alexa S,Beiser [23]
;
Uwe,Völker [19]
;
Tim,Kacprowski [24]
;
Aicha,Soumare [1]
;
Jennifer A,Smith [9]
;
David S,Knopman [25]
;
Zoe,Morris [26]
;
Yicheng,Zhu [27]
;
Jerome I,Rotter [28]
;
Carole,Dufouil [1]
;
Maria,Valdés Hernández [29]
;
Susana,Muñoz Maniega [30]
;
Mark,Lathrop [31]
;
Erik,Boerwinkle [32]
;
Reinhold,Schmidt [33]
;
Masafumi,Ihara [34]
;
Bernard,Mazoyer [35]
;
Qiong,Yang [36]
;
Anne,Joutel [37]
;
Elizabeth,Tournier-Lasserve [38]
;
Lenore J,Launer [39]
;
Ian J,Deary [12]
;
Thomas H,Mosley [40]
;
Philippe,Amouyel [41]
;
Charles S,DeCarli [42]
;
Bruce M,Psaty [43]
;
Christophe,Tzourio [44]
;
Sharon L R,Kardia [9]
;
Hans J,Grabe [11]
;
Alexander,Teumer [45]
;
Cornelia M,van Duijn [46]
;
Helena,Schmidt [17]
;
Joanna M,Wardlaw [29]
;
M Arfan,Ikram [47]
;
Myriam,Fornage [48]
;
Vilmundur,Gudnason [49]
;
Sudha,Seshadri [50]
;
Paul M,Matthews [51]
;
William T,Longstreth [52]
;
Thierry,Couffinhal [2]
;
Stephanie,Debette [53]
作者单位:
University of Bordeaux, INSERM, Bordeaux Population Health Research Centre, Team ELEANOR, UMR 1219, F-33000 Bordeaux, France.
[1]
University of Bordeaux, INSERM, Biologie des Maladies Cardiovasculaires, U1034, F-33600 Pessac, France.
[2]
Department of Epidemiology, Erasmus MC, University Medical Centre, 3015 GD Rotterdam, The Netherlands.;Department of Biomedical Data Sciences, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands.
[3]
Department of Cardiovascular Medicine, Tohoku University Hospital, 1-1, Seiryo, Aoba, Sendai 980-8574, Japan.;Tohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryo, Aoba, Sendai 980-8573, Japan.;Department of Brain Sciences and UK Dementia Research Institute Centre, Imperial College, London, W12 0NN, UK.
[4]
Icelandic Heart Association, 200 Kopavogur, Iceland.
[5]
Department of Biostatistics, Boston University School of Public Health, Boston, MA 02115, USA.
[6]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98195, USA.;Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.
[7]
Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.;Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.
[8]
Department of Epidemiology, School of Public Health, University of Michigan, Michigan, MI 48104, USA.
[9]
Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, 8036 Graz, Austria.;Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, 8036 Graz, Austria.
[10]
German Centre for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, 17489 Greifswald, Germany.;Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17489 Greifswald, Germany.
[11]
Department of Psychology, University of Edinburgh, EH8 9JZ Edinburgh, UK.
[12]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
[13]
Department of Epidemiology, Erasmus MC, University Medical Centre, 3015 GD Rotterdam, The Netherlands.;Department of Radiology and Nuclear Medicine, Erasmus MC, University Medical Centre, 3015 GD Rotterdam, The Netherlands.;Department of Clinical Genetics, Erasmus University Medical Centre Rotterdam, 3015 GD Rotterdam, The Netherlands.
[14]
Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.;The Framingham Heart Study, Framingham, MA 01701, USA.;Department of Neurology, Boston University School of Medicine, Boston, MA 2115, USA.
[15]
National Institute of Neurological Disorders and Stroke Intramural Research Program, Bethesda, MD 20814, USA.
[16]
Institute of Molecular Biology & Biochemistry, Gottfried Schatz Research Centre (for Cell Signalling, Metabolism and Aging), Medical University of Graz, 8036 Graz, Austria.
[17]
Department of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, 17489 Greifswald, Germany.
[18]
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17489 Greifswald, Germany.
[19]
Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh EH8 9AB, UK.;Division of Neuroimaging Sciences, Brain Research Imaging Centre, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.
[20]
Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA.;Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.
[21]
Department of Epidemiology, Erasmus MC, University Medical Centre, 3015 GD Rotterdam, The Netherlands.;Department of Radiology and Nuclear Medicine, Erasmus MC, University Medical Centre, 3015 GD Rotterdam, The Netherlands.
[22]
Department of Biostatistics, Boston University School of Public Health, Boston, MA 02115, USA.;The Framingham Heart Study, Framingham, MA 01701, USA.;Department of Neurology, Boston University School of Medicine, Boston, MA 2115, USA.
[23]
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17489 Greifswald, Germany.;TUM School of Life Sciences Weihenstephan (WZW), Technical University of Munich (TUM), 85354 Freising-Weihenstephan, Germany.
[24]
Mayo Clinic, Rochester, MN 55905, USA.
[25]
Neuroradiology Department, Department of Clinical Neurosciences, Western General Hospital, Edinburgh EH4 2XU, UK.
[26]
Department of Neurology, Peking Union Medical College Hospital, Beijing 100730, China.
[27]
The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA.
[28]
Division of Neuroimaging Sciences, Brain Research Imaging Centre, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.
[29]
Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh EH8 9AB, UK.
[30]
University of McGill Genome Center, Montreal, Quebec H3A 0G1, Canada.
[31]
Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
[32]
Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, 8036 Graz, Austria.
[33]
Department of Neurology, National Cerebral and Cardiovascular Center, Suita, Osaka 564-8565, Japan.
[34]
University of Bordeaux, Institut des Maladies Neurodégénératives, CNRS-CEA UMR 5293, 33000 Bordeaux, France.
[35]
Department of Biostatistics, Boston University School of Public Health, Boston, MA 02115, USA.;The Framingham Heart Study, Framingham, MA 01701, USA.
[36]
Institute of Psychiatry and Neurosciences of Paris, INSERM UMR1266, Université de Paris, France.
[37]
Université de Paris, INSERM UMR-1141 Neurodiderot, Paris F-75019, France.
[38]
Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA.
[39]
Memory Impairment and Neurodegenerative Dementia (MIND) Center, University of Mississippi Medical Center, Jackson, MS 39216, USA.
[40]
University of Lille, INSERM, Institut Pasteur de Lille, UMR1167-RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, F-59000 Lille, France.;LabEx DISTALZ, Institut Pasteur de Lille, 59000 Lille, France.;Department of Epidemiology and Public Health, Centre Hospital University of Lille, F-59000 Lille, France.
[41]
Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, CA 95816, USA.
[42]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98195, USA.;Department of Epidemiology, University of Washington, Seattle, WA, USA.;Department of Health Systems and Population Health, University of Washington, Seattle, WA.
[43]
University of Bordeaux, INSERM, Bordeaux Population Health Research Centre, Team ELEANOR, UMR 1219, F-33000 Bordeaux, France.;CHU de Bordeaux, Pole de santé publique, Service d'information médicale, F-33000 Bordeaux, France.
[44]
Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.
[45]
Department of Biomedical Data Sciences, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands.;Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.
[46]
Department of Biomedical Data Sciences, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands.;Department of Radiology and Nuclear Medicine, Erasmus MC, University Medical Centre, 3015 GD Rotterdam, The Netherlands.
[47]
Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.;Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
[48]
Icelandic Heart Association, 200 Kopavogur, Iceland.;Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.
[49]
Department of Epidemiology, School of Public Health, University of Michigan, Michigan, MI 48104, USA.;The Framingham Heart Study, Framingham, MA 01701, USA.;Department of Neurology, Boston University School of Medicine, Boston, MA 2115, USA.
[50]
Department of Brain Sciences and UK Dementia Research Institute Centre, Imperial College, London, W12 0NN, UK.
[51]
Department of Epidemiology, University of Washington, Seattle, WA, USA.;Department of Neurology, University of Washington, Seattle, WA 98104-2420, USA.
[52]
University of Bordeaux, INSERM, Bordeaux Population Health Research Centre, Team ELEANOR, UMR 1219, F-33000 Bordeaux, France.;Department of Neurology, Boston University School of Medicine, Boston, MA 2115, USA.;CHU de Bordeaux, Department of Neurology, F-33000 Bordeaux, France.
[53]
主题词
动物(Animals);脑缺血(Brain Ischemia);内皮细胞(Endothelial Cells);全基因组关联研究(Genome-Wide Association Study);小鼠(Mice);卒中(Stroke)
DOI
10.1093/brain/awab432
PMID
35511193
发布时间
2023-10-01
- 浏览1

Brain
Brain
1992-2007页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文