Design, synthesis, and bio-evaluation of novel triterpenoid derivatives as anti-HIV-1 compounds.

导出 LinkOut

翻译打印收藏纠错

第一作者： Reon,Takeuchi

第一单位： Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan.

作者： Reon,Takeuchi ^[1] ; Kasumi,Ogihara ^[2] ; Junko,Fujimoto ^[3] ; Kohei,Sato ^[4] ; Nobuyuki,Mase ^[5] ; Kazuhisa,Yoshimura ^[6] ; Shigeyoshi,Harada ^[7] ; Tetsuo,Narumi ^[8]

作者单位： Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan. ^[1] Course of Applied Chemistry and Biochemical Engineering, Department of Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan. ^[2] Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka University, Shizuoka, Japan. ^[3] Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan; Course of Applied Chemistry and Biochemical Engineering, Department of Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan; Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka University, Shizuoka, Japan. ^[4] Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan; Course of Applied Chemistry and Biochemical Engineering, Department of Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan; Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka University, Shizuoka, Japan; Research Institute of Green Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan. ^[5] Institute of Public Health, Bureau of Social Welfare and Public Health, Tokyo Metropolitan Government, 3-24-1 Hyakunin-cho, Shinjuku-ku, Tokyo, Japan; AIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, Japan. ^[6] AIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo, Japan. Electronic address: shigeh@nih.go.jp. ^[7] Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan; Course of Applied Chemistry and Biochemical Engineering, Department of Engineering, Graduate School of Integrated Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan; Department of Applied Chemistry and Biochemical Engineering, Faculty of Engineering, Shizuoka University, Shizuoka, Japan; Research Institute of Green Science and Technology, Shizuoka University, 3-5-1 Johoku, Hamamatsu, Shizuoka, Japan. Electronic address: narumi.tetsuo@shizuoka.ac.jp. ^[8]

关键词 Anti-HIV-1 activity HIV-1 entry inhibitor Neutralizing antibodies SAR study Triterpenoid

主题词抗HIV药(Anti-HIV Agents);HIV融合抑制剂(HIV Fusion Inhibitors);HIV-1(HIV-1);齐墩果酸(Oleanolic Acid);三萜类(Triterpenes)

DOI 10.1016/j.bmcl.2022.128768

PMID 35513221

发布时间 2022-07-05

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交