Identification of Two Non-Peptidergic Small Molecule Inhibitors of CBX2 Binding to K27 Trimethylated Oligonucleosomes.

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作者： Lukas,Lercher ^[1] ; Nina,Simon ^[1] ; Andreas,Bergmann ^[1] ; Marcel,Tauchert ^[1] ; David,Bochmann ^[1] ; Tarig,Bashir ^[1] ; Torsten,Neuefeind ^[1] ; Daniel,Riley ^[2] ; Ben,Danna ^[2] ; Paul,Krawczuk ^[2] ; Vineet,Pande ^[3] ; Aaron,Patrick ^[2] ; Ruth,Steele ^[2] ; Weixue,Wang ^[2] ; Brent,Rupnow ^[4] ; Peter,Tummino ^[2] ; Sujata,Sharma ^[2] ; Michael,Finley ^[2]

作者单位： Proteros Biostructures GmbH, Bunsenstraße 7a, 82152, Planegg, Germany. ^[1] Discovery Sciences, Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, United States. ^[2] Discovery Sciences, Janssen Research and Development, Turnhoutseweg 30, 2340 Beerse, Belgium. ^[3] Oncology Discovery Biology, Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, United States. ^[4]

主题词细胞核(Cell Nucleus);染色质(Chromatin);组蛋白类(Histones);人类(Humans);男(雄)性(Male);前列腺肿瘤(Prostatic Neoplasms)

DOI 10.1016/j.slasd.2022.04.003

PMID 35513262

发布时间 2022-08-17

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SLAS discovery

2022年27卷5期

306-313页

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Identification of Two Non-Peptidergic Small Molecule Inhibitors of CBX2 Binding to K27 Trimethylated Oligonucleosomes.

SLAS discovery

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SLAS discovery

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Identification of Two Non-Peptidergic Small Molecule Inhibitors of CBX2 Binding to K27 Trimethylated Oligonucleosomes.

SLAS discovery

相似文献

SLAS discovery

相关期刊

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