Hair-follicle-associated pluripotent (HAP) stem cells differentiate into mature beating cardiomyocyte sheets on flexible substrates in vitro.

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作者： Nanako,Takaoka ^[1] ; Michiko,Yamane ^[2] ; Koya,Obara ^[3] ; Kyoumi,Shirai ^[4] ; Ryoichi,Aki ^[4] ; Yuko,Hamada ^[4] ; Nobuko,Arakawa ^[4] ; Robert M,Hoffman ^[4] ; Yasuyuki,Amoh ^[4]

作者单位： Department of Dermatology, Kitasato University Grad Sch Med Sci, 1-15-1, Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0374, Japan. dm20016@st.kitasato-u.ac.jp. ^[1] Department of Dermatology, Kitasato University School of Medicine, 1-15-1, Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0374, Japan. dm20016@st.kitasato-u.ac.jp. ^[2] Department of Dermatology, Kitasato University Grad Sch Med Sci, 1-15-1, Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0374, Japan. ^[3] Department of Dermatology, Kitasato University School of Medicine, 1-15-1, Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0374, Japan. ^[4] AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA. ^[5] Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA. ^[6]

关键词 Beating cardiomyocytes Hair-follicle-associated pluripotent stem cells Heart regeneration Long myocardial fibers Mature beating cardiomyocyte sheets Sarcomere structure