首页> Molecular cancer> N<sup>6</sup>-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma.

N<sup>6</sup>-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma.

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第一作者： Yuanlei,Chen

第一单位： Department of Urology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 Qingchun Road, Hangzhou, 310016, China.

作者： Yuanlei,Chen ^[1] ; Zeyi,Lu ^[1] ; Chao,Qi ^[2] ; Chenhao,Yu ^[1] ; Yang,Li ^[1] ; Wang,Huan ^[1] ; Ruyue,Wang ^[1] ; Wenqin,Luo ^[1] ; Danyang,Shen ^[3] ; Lifeng,Ding ^[1] ; Liangliang,Ren ^[1] ; Haiyun,Xie ^[1] ; Dingwei,Xue ^[1] ; Mingchao,Wang ^[1] ; Kangxin,Ni ^[1] ; Liqun,Xia ^[4] ; Jun,Qian ^[5] ; Gonghui,Li ^[6]

作者单位： Department of Urology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 Qingchun Road, Hangzhou, 310016, China. ^[1] Department of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, 310016, China. ^[2] Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. ^[3] Department of Urology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 Qingchun Road, Hangzhou, 310016, China. xialiqun@zju.edu.cn. ^[4] State Key Laboratory of Modern Optical Instrumentations, Centre for Optical and Electromagnetic Research, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, 310058, China. qianjun@zju.edu.cn. ^[5] Department of Urology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 Qingchun Road, Hangzhou, 310016, China. 3193119@zju.edu.cn. ^[6]

关键词 METTL14 N6-methyladenosine RCC Sunitinib-resistance TRAF1