DNA methylation analysis of tumor suppressor genes in liquid biopsy components of early stage NSCLC: a promising tool for early detection.

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作者： Α,Markou ^[1] ; D,Londra ^[2] ; V,Tserpeli ^[2] ; Ι,Kollias ^[2] ; E,Tsaroucha ^[3] ; I,Vamvakaris ^[3] ; K,Potaris ^[3] ; I,Pateras ^[4] ; Α,Kotsakis ^[5] ; V,Georgoulias ^[6] ; Ε,Lianidou ^[2]

作者单位： Analysis of Circulating Tumor Cells (ACTC) Lab, Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece. atmarkou@chem.uoa.gr. ^[1] Analysis of Circulating Tumor Cells (ACTC) Lab, Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, Greece. ^[2] 8th Department of Pulmonary Diseases, 'Sotiria' General Hospital for Chest Diseases, Athens, Greece. ^[3] Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School, National and Kapodistrian University of Athens, Athens, Greece. ^[4] Department of Medical Oncology, University General Hospital of Larissa, Thessaly, Greece. ^[5] First Department of Medical Oncology, Metropolitan General Hospital of Athens, Cholargos, Greece. ^[6]

关键词 Biomarkers CTCs DNA methylation Liquid biopsy NSCLC Tumor suppressor genes cfDNA