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A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues.

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作者单位: Department of Mechanical Engineering, University of Washington, Seattle, WA, USA. akglaser@uw.edu.;Allen Institute for Neural Dynamics, Seattle, WA, USA. akglaser@uw.edu. [1] Department of Mechanical Engineering, University of Washington, Seattle, WA, USA.;Department of Bioengineering, University of Washington, Seattle, WA, USA. [2] Department of Mechanical Engineering, University of Washington, Seattle, WA, USA. [3] Department of Biochemistry and Systems Biomedicine, Graduate School of Medicine, Juntendo University, Tokyo, Japan.;Laboratory for Synthetic Biology, RIKEN Center for Biosystems Dynamics Research, Osaka, Japan. [4] Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.;Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan. [5] Allen Institute for Brain Science, Seattle, WA, USA. [6] Cajal Neuroscience, Seattle, WA, USA. [7] Leica Microsystems, Inc, Buffalo Grove, IL, USA. [8] Department of Restorative Sciences, Texas A&M University, Dallas, TX, USA. [9] Department of Genome Sciences, University of Washington, Seattle, WA, USA. [10] Department of Mechanical Engineering, University of Washington, Seattle, WA, USA.;Department of Laboratory Medicine & Pathology, University of Washington, Seattle, WA, USA. [11] Department of Immunology, University of Washington, Seattle, WA, USA. [12] Department of Urology, University of Washington, Seattle, WA, USA. [13] Department of Biology, University of Washington, Seattle, WA, USA. [14] MDI Biological Laboratory, Bar Harbor, ME, USA. [15] MDI Biological Laboratory, Bar Harbor, ME, USA.;Clinic for Kidney and Hypertension Diseases, Hannover Medical School, Hannover, Germany. [16] Department for Bioelectronics, Vienna University of Technology, Vienna, Austria.;Section for Bioelectronics, Center for Brain Research, Medical University of Vienna, Vienna, Austria. [17] Department of Genome Sciences, University of Washington, Seattle, WA, USA.;Howard Hughes Medical Institute, Seattle, WA, USA.;Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA.;Brotman Baty Institute for Precision Medicine, Seattle, WA, USA. [18] Department of Genome Sciences, University of Washington, Seattle, WA, USA.;Brotman Baty Institute for Precision Medicine, Seattle, WA, USA. [19] Department of Laboratory Medicine & Pathology, University of Washington, Seattle, WA, USA. [20] Allen Institute for Neural Dynamics, Seattle, WA, USA.;Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. [21] Laboratory for Synthetic Biology, RIKEN Center for Biosystems Dynamics Research, Osaka, Japan.;Department of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. [22] Allen Institute for Neural Dynamics, Seattle, WA, USA. [23] Department of Mechanical Engineering, University of Washington, Seattle, WA, USA. jonliu@uw.edu.;Department of Bioengineering, University of Washington, Seattle, WA, USA. jonliu@uw.edu.;Department of Laboratory Medicine & Pathology, University of Washington, Seattle, WA, USA. jonliu@uw.edu. [24]
DOI 10.1038/s41592-022-01468-5
PMID 35545715
发布时间 2024-12-11
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