Meta-analysis of sub-Saharan African studies provides insights into genetic architecture of lipid traits.
作者:
Ananyo,Choudhury [1]
;
Jean-Tristan,Brandenburg [2]
;
Tinashe,Chikowore [3]
;
Dhriti,Sengupta [2]
;
Palwende Romuald,Boua [4]
;
Nigel J,Crowther [5]
;
Godfred,Agongo [6]
;
Gershim,Asiki [7]
;
F Xavier,Gómez-Olivé [8]
;
Isaac,Kisiangani [7]
;
Eric,Maimela [9]
;
Matshane,Masemola-Maphutha [10]
;
Lisa K,Micklesfield [11]
;
Engelbert A,Nonterah [12]
;
Shane A,Norris [11]
;
Hermann,Sorgho [13]
;
Halidou,Tinto [13]
;
Stephen,Tollman [8]
;
Sarah E,Graham [14]
;
Cristen J,Willer [15]
;
AWI-Gen study [16]
;
H3Africa Consortium [17]
;
Scott,Hazelhurst ;
Michèle,Ramsay
作者单位:
Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Ananyo.Choudhury@wits.ac.za.
[1]
Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[2]
Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.;South African Medical Research Council/University of the Witwatersrand Developmental Pathways for Health Research Unit, Department of Paediatrics, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[3]
Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.;Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santè, Nanoro, Burkina Faso.
[4]
Department of Chemical Pathology, National Health Laboratory Service, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[5]
Navrongo Health Research Centre, Ghana Health Service, Navrongo, Ghana.;C.K. Tedam University of Technology and Applied Sciences, Navrongo, Ghana.
[6]
African Population and Health Research Center, Nairobi, Kenya.
[7]
MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[8]
Department of Public Health, School of Health Care Sciences, Faculty of Health Sciences, University of Limpopo, Polokwane, South Africa.
[9]
Department of Pathology and Medical Sciences, School of Health Care Sciences, Faculty of Health Sciences, University of Limpopo, Polokwane, South Africa.
[10]
South African Medical Research Council/University of the Witwatersrand Developmental Pathways for Health Research Unit, Department of Paediatrics, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
[11]
Navrongo Health Research Centre, Ghana Health Service, Navrongo, Ghana.
[12]
Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santè, Nanoro, Burkina Faso.
[13]
Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA.
[14]
Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor, MI, 48109, USA.;Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.;Department of Human Genetics, University of Michigan, Ann Arbor, MI, 48019, USA.
[15]
Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.;School of Electrical and Information Engineering, University of the Witwatersrand, Johannesburg, South Africa.
[16]
Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Michele.Ramsay@wits.ac.za.;Division of Human Genetics, National Health Laboratory Service and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Michele.Ramsay@wits.ac.za.
[17]
主题词
撒哈拉沙漠以南非洲(Africa South of the Sahara);胆固醇, LDL(Cholesterol, LDL);横断面研究(Cross-Sectional Studies);全基因组关联研究(Genome-Wide Association Study);人类(Humans)
DOI
10.1038/s41467-022-30098-w
PMID
35546142
发布时间
2024-12-11
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Nature communications
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