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Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma.

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第一作者： Robyn D,Gartrell

第一单位： Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.

作者： Robyn D,Gartrell ^[1] ; Thomas,Enzler ^[2] ; Pan S,Kim ^[3] ; Benjamin T,Fullerton ^[4] ; Ladan,Fazlollahi ^[5] ; Andrew X,Chen ^[6] ; Hanna E,Minns ^[1] ; Subha,Perni ^[7] ; Stuart P,Weisberg ^[5] ; Emanuelle M,Rizk ^[4] ; Samuel,Wang ^[4] ; Eun Jeong,Oh ^[8] ; Xinzheng V,Guo ^[4] ; Codruta,Chiuzan ^[9] ; Gulam A,Manji ^[4] ; Susan E,Bates ^[4] ; John,Chabot ^[10] ; Beth,Schrope ^[10] ; Michael,Kluger ^[10] ; Jean,Emond ^[10] ; Raul,Rabadán ^[11] ; Donna,Farber ^[12] ; Helen E,Remotti ^[5] ; David P,Horowitz ^[13] ; Yvonne M,Saenger ^[14]

作者单位： Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA. ^[1] Rogel Cancer Center, University of Michigan Medicine, Ann Arbor, MI, USA. ^[2] Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. ^[3] Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. ^[4] Department of Pathology, Columbia University Irving Medical Center, New York, NY, USA. ^[5] Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. ^[6] Harvard Radiation Oncology Program, Massachusetts General Hospital and Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA, USA. ^[7] Mailman School of Public Health, Columbia University, New York, NY, USA. ^[8] Department of Biostatistics, Columbia University Irving Medical Center, New York, NY, USA. ^[9] Department of Surgery, Columbia University Irving Medical Center, New York, NY, USA. ^[10] Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA. ^[11] Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY, USA. ^[12] Department of Radiation Oncology, Columbia University Irving Medical Center, New York, NY, USA. ^[13] Albert Einstein College of Medicine, Columbia University. ^[14]

关键词 T regulatory cells Tumor microenvironment biomarkers tumor-infiltrating lymphocytes

医学主题词癌, 胰腺管(Carcinoma, Pancreatic Ductal);叉头转录因子类(Forkhead Transcription Factors);人类(Humans);黑色素瘤(Melanoma);肿瘤辅助疗法(Neoadjuvant Therapy);胰腺肿瘤(Pancreatic Neoplasms);肿瘤微环境(Tumor Microenvironment)

DOI 10.1080/2162402X.2022.2066767

PMID 35558160

发布时间 2024-01-02

基金项目

KL2 TR001874/TR/NCATS NIH HHS/United States P30 DK132710/DK/NIDDK NIH HHS/United States UL1 TR001873/TR/NCATS NIH HHS/United States

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