Mutational landscape of nasopharyngeal carcinoma based on targeted next-generation sequencing: implications for predicting clinical outcomes.

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作者： Zihan,Zhou ^[1] ; Peifeng,Li ^[2] ; Xianbin,Zhang ^[3] ; Juan,Xu ^[2] ; Jin,Xu ^[2] ; Shui,Yu ^[2] ; Dongqing,Wang ^[2] ; Wei,Dong ^[2] ; Xiujuan,Cao ^[2] ; Hongjiang,Yan ^[2] ; Mingping,Sun ^[2] ; Xiuping,Ding ^[2] ; Jun,Xing ^[2] ; Peng,Zhang ^[2] ; Limin,Zhai ^[2] ; Tingyong,Fan ^[2] ; Shiyu,Tian ^[2] ; Xinhua,Yang ^[2] ; Man,Hu ^[2]

作者单位： Department of Oncology, Weifang Medical University, Weifang, Shandong, China. ^[1] Department of Radiation Oncology and Shandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China. ^[2] Department of Pathology, The 960Th Hospital of PLA, Jinan, China. ^[3] Department of Radiation Oncology and Shandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China. human5770@163.com. ^[4]

关键词 Distant metastasis-free survival Gene Nasopharyngeal carcinoma Risk score Target next-generation sequencing Tumor mutational burden

主题词高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);突变(Mutation);鼻咽肿瘤(Nasopharyngeal Neoplasms);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases)

DOI 10.1186/s10020-022-00479-4

PMID 35562651

发布时间 2022-07-16

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