Global 5mC and 5hmC DNA Levels in Human Sperm Subpopulations with Differentially Protaminated Chromatin in Normo- and Oligoasthenozoospermic Males.

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作者： Marta,Olszewska ^[1] ; Oliwia,Kordyl ^[2] ; Marzena,Kamieniczna ^[1] ; Monika,Fraczek ^[1] ; Piotr,Jędrzejczak ^[3] ; Maciej,Kurpisz ^[1]

作者单位： Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479 Poznan, Poland. ^[1] Faculty of Biology, Adam Mickiewicz University in Poznan, 61-614 Poznan, Poland. ^[2] Division of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-535 Poznan, Poland. ^[3]

关键词 5hmC 5mC male infertility oligozoospermia protamines semen parameters sperm chromatin sperm hydroxymethylation sperm methylation

主题词染色质(Chromatin);DNA(DNA);人类(Humans);不育, 男(雄)性(Infertility, Male);男(雄)性(Male);精子能动性(Sperm Motility);精子(Spermatozoa)

DOI 10.3390/ijms23094516

PMID 35562907

发布时间 2022-05-18

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