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首页> International journal of molecular sciences> Flavonoid Nobiletin Attenuates Cyclophosphamide-Induced Cystitis in Mice through Mechanisms That Involve Inhibition of IL-1β Induced Connexin 43 Upregulation and Gap Junction Communication in Urothelial Cells.

Flavonoid Nobiletin Attenuates Cyclophosphamide-Induced Cystitis in Mice through Mechanisms That Involve Inhibition of IL-1β Induced Connexin 43 Upregulation and Gap Junction Communication in Urothelial Cells.

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作者： Jin,Kono ^[1] ; Masakatsu,Ueda ^[2] ; Atsushi,Sengiku ^[3] ; Sylvia O,Suadicani ^[4] ; Je Tae,Woo ^[5] ; Takashi,Kobayashi ^[1] ; Osamu,Ogawa ^[1] ; Hiromitsu,Negoro ^[6]

作者单位： Department of Urology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan. ^[1] Department of Urology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.;Department of Urology, Shizuoka General Hospital, Shizuoka 420-8527, Japan. ^[2] Department of Urology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.;Sengiku Urology Clinic, Shiga 524-0045, Japan. ^[3] Department of Urology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. ^[4] Department of Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, Kasugai 487-8501, Japan. ^[5] Department of Urology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.;Department of Urology, Faculty of Medicine, University of Tsukuba, Ibaraki 305-8575, Japan. ^[6]

关键词 bladder inflammatory diseases connexin 43 gap junction nobiletin urothelium

主题词动物(Animals);信息交流(Communication);连接蛋白43(Connexin 43);环磷酰胺(Cyclophosphamide);膀胱炎(Cystitis);女(雌)性(Female);黄酮类(Flavones);类黄酮物质(Flavonoids);缝隙接合部(Gap Junctions);白细胞介素1β(Interleukin-1beta);男(雄)性(Male);小鼠(Mice);增量调节(Up-Regulation);尿道上皮(Urothelium)

DOI 10.3390/ijms23095037

PMID 35563427

发布时间 2024-09-23

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International journal of molecular sciences

International journal of molecular sciences

2022年23卷9期

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