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Lung cancer metabolomic data from tumor core biopsies enables risk-score calculation for progression-free and overall survival.

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第一作者： Hunter A,Miller

第一单位： Department of Pharmacology and Toxicology, University of Louisville, Louisville, USA.

作者： Hunter A,Miller ^[1] ; Shesh N,Rai ^[2] ; Xinmin,Yin ^[3] ; Xiang,Zhang ^[3] ; Jason A,Chesney ^[4] ; Victor H,van Berkel ^[5] ; Hermann B,Frieboes ^[6]

作者单位： Department of Pharmacology and Toxicology, University of Louisville, Louisville, USA. ^[1] Department of Pharmacology and Toxicology, University of Louisville, Louisville, USA.;Department of Bioinformatics and Biostatistics, University of Louisville, Louisville, USA.;James Graham Brown Cancer Center, University of Louisville, Louisville, USA. ^[2] Department of Chemistry, University of Louisville, Louisville, USA. ^[3] Department of Pharmacology and Toxicology, University of Louisville, Louisville, USA.;James Graham Brown Cancer Center, University of Louisville, Louisville, USA.;Division of Medical Oncology and Hematology, Department of Medicine, University of Louisville, Louisville, USA.;Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, USA. ^[4] James Graham Brown Cancer Center, University of Louisville, Louisville, USA.;Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, USA. ^[5] Department of Pharmacology and Toxicology, University of Louisville, Louisville, USA. hbfrie01@louisville.edu.;James Graham Brown Cancer Center, University of Louisville, Louisville, USA. hbfrie01@louisville.edu.;Department of Bioengineering, University of Louisville, Lutz Hall 419, Louisville, KY, 40292, USA. hbfrie01@louisville.edu.;Center for Predictive Medicine, University of Louisville, Louisville, USA. hbfrie01@louisville.edu. ^[6]

关键词 Lung cancer Metabolomics Overall survival Progression free survival Risk score calculator Tumor core biopsy

医学主题词活组织检查(Biopsy);无病生存(Disease-Free Survival);人类(Humans);肺肿瘤(Lung Neoplasms);代谢组学(Metabolomics);危险因素(Risk Factors);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1007/s11306-022-01891-x

PMID 35567637

发布时间 2023-05-15

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