Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection.

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第一作者： Yingying,Song

第一单位： Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) and Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Institute of Infectious Diseases and Biosecurity, Shanghai Medical College, Fudan University, Shanghai, 200032, China.

作者： Yingying,Song ^[1] ; Shuyu,Shou ^[1] ; Huimin,Guo ^[2] ; Zixiang,Gao ^[1] ; Nannan,Liu ^[1] ; Yang,Yang ^[1] ; Feifei,Wang ^[1] ; Qiang,Deng ^[1] ; Jing,Liu ^[3] ; Youhua,Xie ^[4]

作者单位： Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) and Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Institute of Infectious Diseases and Biosecurity, Shanghai Medical College, Fudan University, Shanghai, 200032, China. ^[1] Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) and Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Institute of Infectious Diseases and Biosecurity, Shanghai Medical College, Fudan University, Shanghai, 200032, China; Institute for Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, 518112, China; The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, 518112, China. ^[2] Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) and Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Institute of Infectious Diseases and Biosecurity, Shanghai Medical College, Fudan University, Shanghai, 200032, China; Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China. Electronic address: liujing212@fudan.edu.cn. ^[3] Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) and Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Institute of Infectious Diseases and Biosecurity, Shanghai Medical College, Fudan University, Shanghai, 200032, China; Children's Hospital, Fudan University, Shanghai, 201102, China. Electronic address: yhxie@fudan.edu.cn. ^[4]

关键词 BEL7404 Doxycycline (DOX)Hepatitis B virus (HBV)Hepatocyte nuclear factor 4α (HNF4α)Sodium-taurocholate cotransporting polypeptide (NTCP)Tetracycline (Tet)-On

主题词抗病毒药(Antiviral Agents);细胞培养技术(Cell Culture Techniques);乙型肝炎(Hepatitis B);乙型肝炎病毒(Hepatitis B virus);肝细胞(Hepatocytes);人类(Humans);病毒复制(Virus Replication)

DOI 10.1016/j.virs.2022.05.002

PMID 35568375

发布时间 2022-09-10

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Virologica Sinica

2022年37卷4期

558-568页

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Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection.

Virologica Sinica

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Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection.

Virologica Sinica

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Virologica Sinica

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