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首页> Chemico-biological interactions> Diffractaic acid, a novel TrxR1 inhibitor, induces cytotoxicity, apoptosis, and antimigration in human breast cancer cells.

Diffractaic acid, a novel TrxR1 inhibitor, induces cytotoxicity, apoptosis, and antimigration in human breast cancer cells.

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作者： Şeyda Nur,Kalın ^[1] ; Ahmet,Altay ^[2] ; Harun,Budak ^[3]

作者单位： Atatürk University, Science Faculty, Department of Molecular Biology and Genetics, 25240, Erzurum, Turkey; Atatürk University, East Anatolia High Technology Application and Research Center (DAYTAM), 25240, Erzurum, Turkey. ^[1] Erzincan Binali Yıldırım University, Faculty of Science and Arts, Department of Chemistry, 24002, Erzincan, Turkey. ^[2] Atatürk University, Science Faculty, Department of Molecular Biology and Genetics, 25240, Erzurum, Turkey; Atatürk University, East Anatolia High Technology Application and Research Center (DAYTAM), 25240, Erzurum, Turkey. Electronic address: hbudak@atauni.edu.tr. ^[3]

关键词 Breast cancer Diffractaic acid Enzyme activity Expression Lichens Thioredoxin reductase 1

主题词茴香醚类(Anisoles);细胞凋亡(Apoptosis);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);女(雌)性(Female);人类(Humans);硫氧还蛋白还原酶1(Thioredoxin Reductase 1)

DOI 10.1016/j.cbi.2022.109984

PMID 35569514

发布时间 2022-05-30

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