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Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS.

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第一作者： Charlene E,Goh

第一单位： Faculty of Dentistry National University of Singapore Singapore.

作者： Charlene E,Goh ^[1] ; Bruno,Bohn ^[2] ; Clarisse,Marotz ^[3] ; Rebecca,Molinsky ^[2] ; Sumith,Roy ^[4] ; Bruce J,Paster ^[5] ; Ching-Yuan,Chen ^[6] ; Michael,Rosenbaum ^[7] ; Melana,Yuzefpolskaya ^[8] ; Paolo C,Colombo ^[8] ; Moïse,Desvarieux ^[9] ; Panos N,Papapanou ^[6] ; David R,Jacobs ^[2] ; Rob,Knight ^[10] ; Ryan T,Demmer ^[11]

作者单位： Faculty of Dentistry National University of Singapore Singapore. ^[1] Division of Epidemiology and Community Health School of Public Health University of Minnesota Minneapolis MN. ^[2] Department of Pediatrics University of California San Diego La Jolla CA. ^[3] Department of Epidemiology Mailman School of Public Health Columbia University New York NY. ^[4] The Forsyth Institute Cambridge MA.;Department of Oral Medicine, Infection, and Immunity Harvard School of Dental Medicine Boston MA. ^[5] Division of Periodontics Section of Oral, Diagnostic and Rehabilitation Sciences College of Dental Medicine Columbia University New York NY. ^[6] Division of Molecular Genetics Departments of Pediatrics and Medicine Columbia University New York NY. ^[7] Division of Cardiology Department of Medicine New York Presbyterian HospitalColumbia University New York NY. ^[8] Department of Epidemiology Mailman School of Public Health Columbia University New York NY.;INSERM UMR 1153Centre de Recherche Epidemiologie et Statistique Paris Sorbonne Cité (CRESS)METHODS Core Paris France. ^[9] Department of Computer Science & Engineering Jacobs School of Engineering University of California San Diego La Jolla CA.;Department of Bioengineering University of California San Diego La Jolla CA.;Center for Microbiome Innovation University of California San Diego La Jolla CA. ^[10] Division of Epidemiology and Community Health School of Public Health University of Minnesota Minneapolis MN.;Department of Epidemiology Mailman School of Public Health Columbia University New York NY. ^[11]

关键词 16S rNA sequencing blood pressure epidemiology insulin resistance metagenomics nitric oxide oral microbiome

医学主题词成年人(Adult);细菌(Bacteria);心血管疾病(Cardiovascular Diseases);女(雌)性(Female);人类(Humans);男(雄)性(Male);硝酸盐类(Nitrates);一氧化氮(Nitric Oxide);亚硝酸盐类(Nitrites);氮(Nitrogen);二氧化氮(Nitrogen Dioxide);RNA, 核糖体, 16S(RNA, Ribosomal, 16S)

DOI 10.1161/JAHA.121.023038

PMID 35574962

发布时间 2022-07-25

基金项目

R01 DK102932/DK/NIDDK NIH HHS/United States R21 DE022422/DE/NIDCR NIH HHS/United States T32 HL007779/HL/NHLBI NIH HHS/United States R00 DE018739/DE/NIDCR NIH HHS/United States T32 HL007779/HL/NHLBI NIH HHS/United States

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