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Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial.

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第一作者: Sabrina,Paganoni
第一单位: Harvard Medical School, Sean M. Healey and AMG Center for ALS & the Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, Massachusetts, USA spaganoni@mgh.harvard.edu.;Department of PM & R, Spaulding Rehabilitation Hospital, Charlestown, Massachusetts, USA.
作者单位: Harvard Medical School, Sean M. Healey and AMG Center for ALS & the Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, Massachusetts, USA spaganoni@mgh.harvard.edu.;Department of PM & R, Spaulding Rehabilitation Hospital, Charlestown, Massachusetts, USA. [1] Pentara Corporation, Millcreek, Utah, USA. [2] Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Swedish Neuroscience Institute, Seattle, Washington, USA. [4] Department of Neurology, Hennepin Healthcare, Minneapolis, Minnesota, USA. [5] Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA. [6] Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA. [7] Department of Neurology, University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, USA. [8] Department of Neurology, Ohio State University, Columbus, Ohio, USA. [9] Department of Neurology, College of Medicine, University of Florida, Gainesville, Florida, USA. [10] Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA. [11] ALS Clinic, Texas Neurology, Dallas, Texas, USA. [12] Department of Neurology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA. [13] Department of Neurology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA. [14] Department of Neurology, Johns Hopkins University Brain Science Institute, Baltimore, Maryland, USA. [15] Department of Neurology, University of Kentucky, Lexington, Kentucky, USA. [16] California Pacific Medical Center Research Institute and Forbes Norris MDA/ALS Research and Treatment Center, San Francisco, California, USA. [17] Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, USA. [18] Hope Center for Neurological Disorders, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri, USA. [19] Department of Neurology, Mount Sinai Beth Israel, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [20] Department of Neurology, University of South Florida Morsani College of Medicine, Tampa, Florida, USA. [21] Department of Neurology, Emory University, Atlanta, Georgia, USA. [22] Department of Neurology, Ochsner Health System, New Orleans, Louisiana, USA. [23] Department of Neurology, University of Iowa Health Care, Iowa City, Iowa, USA. [24] Department of Neurology, University of California Irvine School of Medicine, Irvine, California, USA. [25] Neurology Associates, Lincoln, Nebraska, USA. [26] Harvard Medical School, Sean M. Healey and AMG Center for ALS & the Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, Massachusetts, USA. [27] Worldwide Clinical Trials, Research Triangle Park, North Carolina, USA.;Formerly With Gregory W. Fulton ALS Center, Barrow Neurological Institute, Phoenix, Arizona, USA. [28] Amylyx Pharmaceuticals Inc, Cambridge, Massachusetts, USA. [29] Department of Neurology, Genetics and Aging Research Unit, McCance Center for Brain Health, Massachusetts General Hospital, Harvard University, Boston, Massachusetts, USA. [30] Carl M. Loeb University Professor Emeritus and Chair of the Society of Fellows at Harvard, Harvard University, Cambridge, Massachusetts, USA. [31]
DOI 10.1136/jnnp-2022-329024
PMID 35577511
发布时间 2024-09-01
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Journal of neurology, neurosurgery, and psychiatry

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