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首页> Nature communications> Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy.

Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy.

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作者： Liangliang,Dai ^[1] ; Mengjiao,Yao ^[2] ; Zhenxiang,Fu ^[3] ; Xiang,Li ^[1] ; Xinmin,Zheng ^[3] ; Siyu,Meng ^[3] ; Zhang,Yuan ^[1] ; Kaiyong,Cai ^[1] ; Hui,Yang ^[4] ; Yanli,Zhao ^[5]

作者单位： Institute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, PR China. ^[1] Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore. ^[2] School of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, PR China. ^[3] Key Laboratory of Biorheological Science and Technology, Ministry of Education College of Bioengineering, Chongqing University, Chongqing, 400044, PR China. kaiyong_cai@cqu.edu.cn. ^[4] School of Life Sciences, Northwestern Polytechnical University, Xi'an, 710072, PR China. kittyyh@nwpu.edu.cn. ^[5] Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore. zhaoyanli@ntu.edu.sg. ^[6]

主题词细胞系, 肿瘤(Cell Line, Tumor);葡糖氧化酶(Glucose Oxidase);人类(Humans);免疫疗法(Immunotherapy);吲哚胺-吡咯2,3-双加氧酶(Indoleamine-Pyrrole 2,3,-Dioxygenase);纳米粒子(Nanoparticles);纳米技术(Nanotechnology);肿瘤(Neoplasms);活性氧(Reactive Oxygen Species);肿瘤微环境(Tumor Microenvironment)

DOI 10.1038/s41467-022-30436-y

PMID 35577812

发布时间 2022-07-16

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Nature communications

Nature communications

2022年13卷1期

2688页

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