首页> Cytotherapy> Comparable transforming growth factor beta-mediated immune suppression in ex vivo-expanded natural killer cells from cord blood and peripheral blood: implications for adoptive immunotherapy.

Comparable transforming growth factor beta-mediated immune suppression in ex vivo-expanded natural killer cells from cord blood and peripheral blood: implications for adoptive immunotherapy.

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第一作者： Kajal,Chaudhry

第一单位： Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC, USA.

作者： Kajal,Chaudhry ^[1] ; Ehsan,Dowlati ^[2] ; Mark D,Long ^[3] ; Ashley,Geiger ^[1] ; Haili,Lang ^[1] ; Eduardo C,Gomez ^[3] ; Nethaji,Muniraj ^[1] ; Carlos E,Sanchez ^[1] ; Prashant K,Singh ^[4] ; Song,Liu ^[3] ; Catherine M,Bollard ^[5] ; Conrad Russell Y,Cruz ^[6]

作者单位： Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC, USA. ^[1] Department of Neurosurgery, Georgetown University Medical Center, Washington, DC, USA. ^[2] Department of Biostatistics and Bioinformatics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA. ^[3] Genomics Shared Resource, Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA. ^[4] Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC, USA; George Washington University Cancer Center, George Washington University, Washington, DC, USA. Electronic address: cbollard@childrensnational.org. ^[5] Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC, USA; George Washington University Cancer Center, George Washington University, Washington, DC, USA. Electronic address: ccruz@childrensnational.org. ^[6]

关键词 Cord blood NK cells NK-cell immunotherapy Peripheral blood NK cells TGF-β

医学主题词细胞系, 肿瘤(Cell Line, Tumor);胎血(Fetal Blood);移植物抗宿主病(Graft vs Host Disease);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);杀伤细胞, 天然(Killer Cells, Natural);转化生长因子β(Transforming Growth Factor beta)

DOI 10.1016/j.jcyt.2022.04.001

PMID 35589475

发布时间 2025-10-31

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准确一般字义偏差语意偏离译文作用小提交