The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations.
作者:
Zhe,Wang [1]
;
Shing Wan,Choi [2]
;
Nathalie,Chami [3]
;
Eric,Boerwinkle [1]
;
Myriam,Fornage [2]
;
Susan,Redline [4]
;
Joshua C,Bis [5]
;
Jennifer A,Brody [6]
;
Bruce M,Psaty [7]
;
Wonji,Kim [8]
;
Merry-Lynn N,McDonald [9]
;
Elizabeth A,Regan [9]
;
Edwin K,Silverman [9]
;
Ching-Ti,Liu [10]
;
Ramachandran S,Vasan [11]
;
Rita R,Kalyani [12]
;
Rasika A,Mathias [13]
;
Lisa R,Yanek [14]
;
Donna K,Arnett [15]
;
Anne E,Justice [16]
;
Kari E,North [17]
;
Robert,Kaplan [18]
;
Susan R,Heckbert [19]
;
Mariza,de Andrade [20]
;
Xiuqing,Guo [20]
;
Leslie A,Lange [20]
;
Stephen S,Rich [21]
;
Jerome I,Rotter [22]
;
Patrick T,Ellinor [23]
;
Steven A,Lubitz [24]
;
John,Blangero [10]
;
M Benjamin,Shoemaker [25]
;
Dawood,Darbar [26]
;
Mark T,Gladwin [27]
;
Christine M,Albert [28]
;
Daniel I,Chasman [29]
;
Rebecca D,Jackson [27]
;
Charles,Kooperberg [30]
;
Alexander P,Reiner [31]
;
Paul F,O'Reilly [30]
;
Ruth J F,Loos [31]
作者单位:
The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
[1]
The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
[2]
Department of Genetics and Genomic Sciences, Icahn School of Medicine, Mount Sinai, New York, NY, United States.
[3]
Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, United States.
[4]
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, United States.
[5]
Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, United States.
[6]
Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.
[7]
Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
[8]
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, United States.
[9]
Department of Epidemiology, University of Washington, Seattle, WA, United States.
[10]
Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, United States.
[11]
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
[12]
Division of Rheumatology, Department of Medicine, National Jewish Health, Denver, CO, United States.
[13]
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.
[14]
Department of Medicine, Harvard Medical School, Boston, MA, United States.
[15]
Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States.
[16]
National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, United States.
[17]
Section of Preventive Medicine and Epidemiology, Evans Department of Medicine, Boston University School of Medicine, Boston, MA, United States.
[18]
Whitaker Cardiovascular Institute and Cardiology Section, Evans Department of Medicine, Boston University School of Medicine, Boston, MA, United States.
[19]
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
[20]
College of Public Health, University of Kentucky, Lexington, KY, United States.
[21]
Department of Population Health Services, Geisinger Health, Danville, PA, United States.
[22]
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
[23]
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, United States.
[24]
Kaiser Permanente Washington Health Research Institute, Seattle, WA, United States.
[25]
Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, United States.
[26]
The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, United States.
[27]
Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anchutz Medical Camus, Aurora, CA, United States.
[28]
Center for Public Health Genomics, University of Virginia, Charlottesville, VA, United States.
[29]
Cardiovascular Disease Initiative, The Broad Institute of MIT and Harvard, Cambridge, MA, United States.
[30]
Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, United States.
[31]
Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, United States.
[32]
Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States.
[33]
Division of Cardiology, University of Illinois at Chicago, Chicago, IL, United States.
[34]
Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
[35]
Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
[36]
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, United States.
[37]
Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, The Ohio State University, Columbus, OH, United States.
[38]
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.
[39]
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
[40]
主题词
基因频率(Gene Frequency);遗传变异(Genetic Variation);全基因组关联研究(Genome-Wide Association Study);人类(Humans);肥胖症(Obesity)
DOI
10.3389/fendo.2022.863893
PMID
35592775
发布时间
2023-08-02
- 浏览0
Frontiers in endocrinology
863893页
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