Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible?

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作者： Susanne M,Mesoy ^[1] ; Matthew,Bridgland-Taylor ^[2] ; Sarah C R,Lummis ^[1]

作者单位： Department of Biochemistry, University of Cambridge, University of Cambridge, Cambridge, United Kingdom. ^[1] Clinical Pharmacology and Safety Sciences, Biopharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom. ^[2]

关键词 Cys-loop receptor M4 aromatic interaction mutagenesis nACh receptor

DOI 10.3389/fphys.2022.850782

PMID 35600303

发布时间 2023-07-05

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Frontiers in physiology

2022年13卷

850782页

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Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible?

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Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible?

Frontiers in physiology

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Frontiers in physiology

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