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Fusing spheroids to aligned μ-tissues in a heart-on-chip featuring oxygen sensing and electrical pacing capabilities.

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第一作者： Oliver,Schneider

第一单位： Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany.

作者： Oliver,Schneider ^[1] ; Alessia,Moruzzi ^[2] ; Stefanie,Fuchs ^[3] ; Alina,Grobel ^[1] ; Henrike S,Schulze ^[1] ; Torsten,Mayr ^[3] ; Peter,Loskill ^[4]

作者单位： Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany. ^[1] NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.;Department for Microphysiological Systems, Institute of Biomedical Engineering, Eberhard Karls University Tübingen, Tübingen, Germany. ^[2] Institute for Analytical Chemistry and Food Chemistry, Graz University of Technology, Graz, Austria. ^[3] NMI Natural and Medical Sciences Institute at the University of Tübingen, Reutlingen, Germany.;Department for Microphysiological Systems, Institute of Biomedical Engineering, Eberhard Karls University Tübingen, Tübingen, Germany.;3R-Center for In vitro Models and Alternatives to Animal Testing, Eberhard Karls University Tübingen, Tübingen, Germany. ^[4]

关键词 CMs, Cardiomyocytes Electrical stimulation HoC, Heart-on-Chip Metabolism Microphysiological systems Noninvasive readouts OoC, Organ-on-Chip Optical sensors Organ-on-Chip hiPSCs, human induced pluripotent stem cells

DOI 10.1016/j.mtbio.2022.100280

PMID 35601892

发布时间 2022-07-16

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Fusing spheroids to aligned μ-tissues in a heart-on-chip featuring oxygen sensing and electrical pacing capabilities.

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Fusing spheroids to aligned μ-tissues in a heart-on-chip featuring oxygen sensing and electrical pacing capabilities.

Materials today. Bio

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