PET Imaging of Bromodomain and Extra-Terminal Domain Inhibitors for the Noninvasive Assessment of Metabolic Changes in the Liver and Brain of Early-Stage Alcoholic Liver Disease.

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第一作者： Zude,Chen

第一单位： Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510230, China.

作者： Zude,Chen ^[1] ; Riwei,Yang ^[2] ; Yulong,Xu ^[1] ; Leqi,Liang ^[2] ; Shan,Ao ^[1] ; Zuomin,Wang ^[1] ; Ping,Bai ^[1] ; Di,Gu ^[2] ; Xiaolu,Duan ^[1] ; Yongda,Liu ^[1] ; Wen,Zhong ^[1] ; Peng,Xu ^[1] ; Tuo,Deng ^[1] ; Guohua,Zeng ^[1] ; Changning,Wang ^[1]

作者单位： Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510230, China. ^[1] Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, United States. ^[2]

关键词 PET imaging [11C]CW22 alcoholic liver disease bromodomain and extra-terminal domain

主题词动物(Animals);脑(Brain);氟脱氧葡萄糖F18(Fluorodeoxyglucose F18);肝疾病, 酒精性(Liver Diseases, Alcoholic);小鼠(Mice);正电子发射断层显像术(Positron-Emission Tomography)

DOI 10.1021/acs.molpharmaceut.2c00143

PMID 35604773

发布时间 2022-07-13

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