<b>GPR83 engages endogenous peptides from two distinct precursors to elicit differential signaling</b>.

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作者： Seshat M,Mack ^[1] ; Ivone,Gomes ^[2] ; Amanda K,Fakira ^[3] ; Mariana L,Duarte ^[4] ; Achla,Gupta ^[4] ; Lloyd,Fricker ^[5] ; Lakshmi A,Devi ^[6]

作者单位： Department of Pharmacological Sciences, Mount Sinai School of Medicine, United States lakshmi.devi@mssm.edu. ^[1] Department of Pharmacology & Systems Therapeutics, Mount Sinai School of Medicine, United States. ^[2] Department of Biomedical Sciences, Cooper Medical School of Rowan University, United States. ^[3] Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, United States. ^[4] Department of Molecular Pharmacology, Albert Einstein College of Medicine, United States. ^[5] Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, United States lakshmi.devi@mssm.edu. ^[6]

关键词 Biased agonism G protein coupled signaling G proteins g protein-coupled receptors (GPCRS)

DOI 10.1124/molpharm.122.000487

PMID 35605991

发布时间 2025-02-13

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