UPF1 promotes rapid degradation of m<sup>6</sup>A-containing RNAs.

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作者： Sung Ho,Boo ^[1] ; Hongseok,Ha ^[1] ; Yujin,Lee ^[1] ; Min-Kyung,Shin ^[1] ; Sena,Lee ^[1] ; Yoon Ki,Kim ^[2]

作者单位： Creative Research Initiatives Center for Molecular Biology of Translation, Korea University, Seoul 02841, Republic of Korea; Division of Life Sciences, Korea University, Seoul 02841, Republic of Korea. ^[1] Creative Research Initiatives Center for Molecular Biology of Translation, Korea University, Seoul 02841, Republic of Korea; Division of Life Sciences, Korea University, Seoul 02841, Republic of Korea. Electronic address: yk-kim@korea.ac.kr. ^[2]

关键词 CP: Molecular biology N6-methyladenosine PNRC2 RNA modification UPF1 YTHDF2 m(6)A mRNA degradation nonsense-mediated mRNA decay

主题词 RNA(RNA);RNA解螺旋酶类(RNA Helicases);RNA稳定性(RNA Stability);RNA, 信使(RNA, Messenger);反式激活因子类(Trans-Activators);转录因子(Transcription Factors)

DOI 10.1016/j.celrep.2022.110861

PMID 35613594

发布时间 2022-09-06

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