首页> Biomolecules> Multiple Mutations in the Non-Ordered Red Ω-Loop Enhance the Membrane-Permeabilizing and Peroxidase-like Activity of Cytochrome <i>c</i>.

Multiple Mutations in the Non-Ordered Red Ω-Loop Enhance the Membrane-Permeabilizing and Peroxidase-like Activity of Cytochrome <i>c</i>.

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第一作者： Rita V,Chertkova

第一单位： Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.

作者： Rita V,Chertkova ^[1] ; Alexander M,Firsov ^[2] ; Nadezda A,Brazhe ^[3] ; Evelina I,Nikelshparg ^[3] ; Zhanna V,Bochkova ^[4] ; Tatyana V,Bryantseva ^[5] ; Marina A,Semenova ^[1] ; Adil A,Baizhumanov ^[3] ; Elena A,Kotova ^[2] ; Mikhail P,Kirpichnikov ^[5] ; Georgy V,Maksimov ^[6] ; Yuriy N,Antonenko ^[2] ; Dmitry A,Dolgikh ^[5]

作者单位： Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia. ^[1] Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia. ^[2] Biophysics Department, Biological Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia. ^[3] Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.;Biophysics Department, Biological Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia. ^[4] Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.;Biology Department, Lomonosov Moscow State University, 119899 Moscow, Russia. ^[5] Biophysics Department, Biological Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia.;Federal State Autonomous Educational Institution of Higher Education "National Research Technological University "MISiS"", 119049 Moscow, Russia. ^[6]

关键词 cardiolipin heme liposome leakage mitochondrial cytochrome c peroxidase activity red Ω-loop of cytochrome c resonance Raman spectroscopy surface-enhanced Raman spectroscopy

医学主题词抗氧化剂(Antioxidants);心磷脂质类(Cardiolipins);细胞色素c类(Cytochromes c);血红素(Heme);脂质体(Liposomes);突变(Mutation);过氧化物酶类(Peroxidases)

DOI 10.3390/biom12050665

PMID 35625593

发布时间 2024-08-29

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