Lactoferrin Inhibition of the Complex Formation between ACE2 Receptor and SARS CoV-2 Recognition Binding Domain.

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第一作者： Roberta,Piacentini

第一单位： Department of Biochemistry, Sapienza University, Piazzale Aldo Moro 5, 00185 Rome, Italy.

作者： Roberta,Piacentini ^[1] ; Laura,Centi ^[2] ; Mattia,Miotto ^[1] ; Edoardo,Milanetti ^[2] ; Lorenzo,Di Rienzo ^[3] ; Martina,Pitea ^[2] ; Paolo,Piazza ^[3] ; Giancarlo,Ruocco ^[2] ; Alberto,Boffi ^[2] ; Giacomo,Parisi ^[4]

作者单位： Department of Biochemistry, Sapienza University, Piazzale Aldo Moro 5, 00185 Rome, Italy. ^[1] Center of Life Nano and Neuro Science, Institute of Italian Technology, Viale Regina Elena 291, 00181 Rome, Italy. ^[2] Department of Physics, Sapienza University, Piazzale Aldo Moro 5, 00185 Rome, Italy. ^[3] D-Tails s.r.l., Via di Torre Rossa 66, 00165 Rome, Italy. ^[4] EDIF Instruments s.r.l., Via Ardeatina 132, 00147 Rome, Italy. ^[5]

关键词 SARS-CoV-2 receptor-binding domain (RBD)angiotensin-converting enzyme 2 (ACE2)biolayer interferometry kinetic analysis lactoferrin nanoparticle enhanced turbidimetry

主题词人类(Humans);乳铁蛋白(Lactoferrin);肽基二肽酶A(Peptidyl-Dipeptidase A);蛋白质相互作用域和基序(Protein Interaction Domains and Motifs)

DOI 10.3390/ijms23105436

PMID 35628247

发布时间 2022-07-16

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