Analysis of microbiome in gastrointestinal stromal tumors: Looking for different players in tumorigenesis and novel therapeutic options.

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第一作者： Gloria,Ravegnini

第一单位： Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.

作者： Gloria,Ravegnini ^[1] ; Bruno,Fosso ^[2] ; Riccardo,Ricci ^[3] ; Francesca,Gorini ^[1] ; Silvia,Turroni ^[1] ; Cesar,Serrano ^[4] ; Daniel F,Pilco-Janeta ^[5] ; Qianqian,Zhang ^[3] ; Federica,Zanotti ^[1] ; Mariangela,De Robertis ^[6] ; Margherita,Nannini ^[7] ; Maria Abbondanza,Pantaleo ^[7] ; Patrizia,Hrelia ^[1] ; Sabrina,Angelini ^[8]

作者单位： Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy. ^[1] Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council, Bari, Italy.;Department of Biosciences, Biotechnology and Biopharmaceutics (DBBB), University of Bari "A. Moro", Bari, Italy. ^[2] Department of Pathology, Catholic University, Rome, Italy. ^[3] Sarcoma Translational Research Laboratory, Vall d'Hebron University Hospital, Barcelona, Spain. ^[4] Sarcoma Translational Research Laboratory, Vall d'Hebron University Hospital, Barcelona, Spain.;Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. ^[5] Department of Biosciences, Biotechnology and Biopharmaceutics (DBBB), University of Bari "A. Moro", Bari, Italy. ^[6] Department of Experimental, Diagnostic and Specialized Medicine (DIMES), Alma Mater Studiorum, University of Bologna, Bologna, Italy.;Medical Oncology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. ^[7] Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.;Health Sciences and Technologies-Interdepartmental Center for Industrial Research (CIRI-SDV), University of Bologna, Bologna, Italy. ^[8]

关键词 GIST carcinogenesis microGIST microbiome tumor evolution

主题词细胞转化, 肿瘤(Cell Transformation, Neoplastic);胃肠肿瘤(Gastrointestinal Neoplasms);胃肠道间质肿瘤(Gastrointestinal Stromal Tumors);人类(Humans);突变(Mutation);原癌基因蛋白质类c-kit(Proto-Oncogene Proteins c-kit)

DOI 10.1111/cas.15441

PMID 35633186

发布时间 2022-08-10

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