Altered mucosal immunity in HIV-positive colon adenoma: decreased CD4<sup>+</sup> T cell infiltration is correlated with nadir but not current CD4<sup>+</sup> T cell blood counts.

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作者： Yasuo,Matsubara ^[1] ; Yasunori,Ota ^[2] ; Yukihisa,Tanaka ^[2] ; Tamami,Denda ^[2] ; Yasuki,Hijikata ^[3] ; Narikazu,Boku ^[4] ; Lay Ahyoung,Lim ^[5] ; Yoshihiro,Hirata ^[4] ; Giichiro,Tsurita ^[6] ; Eisuke,Adachi ^[7] ; Hiroshi,Yotsuyanagi ^[7]

作者单位： Department of Oncology and General Medicine, IMSUT Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. ma-yasu@ims.u-tokyo.ac.jp. ^[1] Department of Diagnostic Pathology, IMSUT Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. ^[2] Department of Palliative Medicine/Advanced Clinical Oncology, IMSUT Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. ^[3] Department of Oncology and General Medicine, IMSUT Hospital, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. ^[4] Department of Research, Kitasato Institute Hospital, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8642, Japan. ^[5] Department of Surgery, IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. ^[6] Department of Infectious Diseases and Applied Immunology, IMSUT Hospital of the Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. ^[7]

关键词 CD4+ T cells Colon adenomas HIV Tumor microenvironment