Creation of a Yeast Strain with Co-Translationally Acylated Nucleosomes.

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第一作者： Dan,Wu

第一单位： State Key Laboratory of Natural and Biomimetic Drugs, Chemical Biology Center, Department of Molecular and Cellular, Pharmacology, Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China.

作者： Dan,Wu ^[1] ; Yunfeng,Zhang ^[2] ; Zhiheng,Tang ^[3] ; Xiaoxu,Chen ^[1] ; Xinyu,Ling ^[1] ; Longtu,Li ^[4] ; Wenbing,Cao ^[1] ; Wei,Zheng ^[1] ; Jiale,Wu ^[4] ; Hongting,Tang ^[2] ; Xiaoyun,Liu ^[3] ; Xiaozhou,Luo ^[2] ; Tao,Liu ^[5]

作者单位： State Key Laboratory of Natural and Biomimetic Drugs, Chemical Biology Center, Department of Molecular and Cellular, Pharmacology, Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China. ^[1] Center for Synthetic Biochemistry, Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. ^[2] Department of Microbiology, School of Basic Medical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China. ^[3] Key Laboratory of Protein and Plant Gene Research, School of Life Sciences and Peking-Tsinghua Center for Life Science, Peking University, Beijing, 100871, China. ^[4] CAS Key Laboratory of Quantitative Engineering Biology, Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. ^[5]

关键词 Co-Translational Modification Crotonylation Genetic Code Expansion Histone Non-Canonical Amino Acid

主题词乙酰化作用(Acetylation);组蛋白类(Histones);赖氨酸(Lysine);核小体(Nucleosomes);蛋白质加工, 转译后(Protein Processing, Post-Translational);酿酒酵母菌(Saccharomyces cerevisiae)

DOI 10.1002/anie.202205570

PMID 35644909

发布时间 2022-07-28

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