换一批
换一批Autophagy enhanced by curcumin ameliorates inflammation in atherogenesis <i>via</i> the TFEB-P300-BRD4 axis.
第一作者：
Xuesong,Li
第一单位：
Key Laboratory of Cardiovascular and Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
作者：
关键词
ATG5, autophagy-related 5Acetyl-H3, acetyl-histone 3AtherosclerosisAutophagyBET, bromodomain and extra-terminalBRD4BRD4, bromodomain protein 4CQ, chloroquineCVDs, cardiovascular diseasesChIP, chromatin immunoprecipitationCur, curcuminCurcuminDil-ox-LDL, 1,1′-dioctadecyl-3,3,3′,3′-tetramethy-lindocarbocyanine perchlorate labeled oxidized low-density lipoproteinFCs, foam cellsHFD, high-fat dietIL-1β, interleukin 1βInflammationLIR, LC3-interacting regionMCP-1, monocyte chemotactic protein 1MacrophageNAC, N-acetyl-l-cysteineORO, Oil red OP300ROS, reactive oxygen speciesRe-ChIP, re-chromatin immunoprecipitationSE, super-enhancerTFEBTFEB, transcription factor EBTNF-α, tumor necrosis factor αmTORC1, mammalian target of rapamycin complex 1ox-LDL, oxidized low-density lipoproteinqRT-PCR, quantitative real-time polymerase chain reactionsiRNAs, small interference RNAs
DOI
10.1016/j.apsb.2021.12.014
PMID
35646539
发布时间
2022-07-16
- 浏览0
Acta pharmaceutica Sinica. B
2022年12卷5期
2280-2299页
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
