<i>Dendrocalamus latiflorus</i> and its component rutin exhibit glucose-lowering activities by inhibiting hepatic glucose production <i>via</i> AKT activation.

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第一作者： Kun,Luo

第一单位： State Key Laboratory of Membrane Biology, School of Medicine, Tsinghua University, Beijing 100084, China.;Medical Systems Biology Research Center, School of Medicine, Tsinghua University, Beijing 100084, China.

作者： Kun,Luo ^[1] ; Wenting,Huang ^[1] ; Liansheng,Qiao ^[1] ; Xiaoling,Zhang ^[2] ; Di,Yan ^[3] ; Zhiyu,Ning ^[1] ; Chengmei,Ma ^[2] ; Honglei,Dang ^[2] ; Dong,Wang ^[3] ; Hongyan,Guo ^[2] ; Lan,Xie ^[4] ; Jing,Cheng ^[5]

作者单位： State Key Laboratory of Membrane Biology, School of Medicine, Tsinghua University, Beijing 100084, China.;Medical Systems Biology Research Center, School of Medicine, Tsinghua University, Beijing 100084, China. ^[1] National Engineering Research Center for Beijing Biochip Technology, Beijing 102206, China. ^[2] School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. ^[3] State Key Laboratory of Membrane Biology, School of Medicine, Tsinghua University, Beijing 100084, China.;Medical Systems Biology Research Center, School of Medicine, Tsinghua University, Beijing 100084, China.;National Engineering Research Center for Beijing Biochip Technology, Beijing 102206, China. ^[4] State Key Laboratory of Membrane Biology, School of Medicine, Tsinghua University, Beijing 100084, China.;Medical Systems Biology Research Center, School of Medicine, Tsinghua University, Beijing 100084, China.;National Engineering Research Center for Beijing Biochip Technology, Beijing 102206, China.;School of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. ^[5]

关键词 AKT DLE, Dendrocalamus latiflorus leaf extract Dendrocalamus latiflorus leaf extract FOXO1 FOXO1, forkhead box O1 G6PC, glucose 6 phosphatase Gene expression profiling IGF1R IGF1R, insulin growth factor 1 receptor Network pharmacology PCK1, phosphoenolpyruvate carboxykinase 1 PIN, protein interaction network PKB/AKT, protein kinase B Rutin T2DM, type 2 diabetes mellitus Type 2 diabetes mellitus

DOI 10.1016/j.apsb.2021.11.017

PMID 35646547

发布时间 2022-07-16

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Acta pharmaceutica Sinica. B

2022年12卷5期

2239-2251页

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<i>Dendrocalamus latiflorus</i> and its component rutin exhibit glucose-lowering activities by inhibiting hepatic glucose production <i>via</i> AKT activation.

Acta pharmaceutica Sinica. B

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Acta pharmaceutica Sinica. B

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<i>Dendrocalamus latiflorus</i> and its component rutin exhibit glucose-lowering activities by inhibiting hepatic glucose production <i>via</i> AKT activation.

Acta pharmaceutica Sinica. B

相似文献

Acta pharmaceutica Sinica. B

相关期刊

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