Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants.

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作者： Jenny E,Hernandez-Davies ^[1] ; Emmanuel P,Dollinger ^[2] ; Egest J,Pone ^[1] ; Jiin,Felgner ^[1] ; Li,Liang ^[1] ; Shirin,Strohmeier ^[3] ; Sharon,Jan ^[1] ; Tyler J,Albin ^[4] ; Aarti,Jain ^[1] ; Rie,Nakajima ^[1] ; Algimantas,Jasinskas ^[1] ; Florian,Krammer ^[5] ; Aaron,Esser-Kahn ^[6] ; Philip L,Felgner ^[1] ; Qing,Nie ^[2] ; D Huw,Davies ^[7]

作者单位： Vaccine Research and Development Center, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, CA, 92697, USA. ^[1] Department of Mathematics, University of California, Irvine, CA, 92697, USA. ^[2] Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ^[3] Department of Chemistry, University of California, Irvine, CA, 92697, USA.;Avidity Biosciences, San Diego, CA, 92121, USA. ^[4] Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.;Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ^[5] Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, 60637, USA. ^[6] Vaccine Research and Development Center, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, CA, 92697, USA. ddavies@uci.edu. ^[7]