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Association of Tumor Mutational Burden with Efficacy of Pembrolizumab±Chemotherapy as First-Line Therapy for Gastric Cancer in the Phase III KEYNOTE-062 Study.

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作者单位: Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. [1] Department of Digestive Oncology, University Hospitals Gasthuisberg and University of Leuven, Leuven, Belgium. [2] Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. [3] Department of Internal Medicine, Yale Cancer Center, Smilow Cancer Hospital, New Haven, Connecticut. [4] Department of Medical Oncology, Latvian Oncology Center Rakus Gailezers, Riga, Latvia. [5] Department of Hematology and Oncology, Pontifical Catholic University of Chile, Santiago, Chile. [6] Department of Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. [7] Department of Medicine, Samsung Medical Center, Seoul, Republic of Korea. [8] Department of Medical Oncology, Angeles Medical Group, Guatemala City, Guatemala. [9] Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California. [10] David Geffen School of Medicine at the University of California, Los Angeles, California. [11] Merck & Co., Inc., Rahway, New Jersey. [12] Vall d'Hebron Hospital Campus and Institute of Oncology (VHIO), IOB-Quiron, UVic-UCC, Barcelona, Spain. [13] Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan. [14] Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya, Japan. [15] Department of Oncology and Radiotherapy, Maria Skłodowska-Curie National Cancer Research Institute, Warsaw, Poland. [16]
DOI 10.1158/1078-0432.CCR-22-0121
PMID 35657979
发布时间 2022-09-09
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Clinical cancer research : an official journal of the American Association for Cancer Research

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