Optimizing Foundational Therapies in Patients With HFrEF: How Do We Translate These Findings Into Clinical Care?

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作者： Abhinav,Sharma ^[1] ; Subodh,Verma ^[2] ; Deepak L,Bhatt ^[3] ; Kim A,Connelly ^[4] ; Elizabeth,Swiggum ^[5] ; Muthiah,Vaduganathan ^[6] ; Shelley,Zieroth ^[7] ; Javed,Butler ^[8]

作者单位： Division of Cardiology, McGill University Health Centre, Montréal, Quebec, Canada. ^[1] Division of Cardiac Surgery, St Michael's Hospital, and Departments of Surgery, and Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada. ^[2] Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA. ^[3] Keenan Research Center for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada. ^[4] Division of Cardiology, Royal Jubilee Hospital and Department of Medicine, University of British Columbia, Victoria, British Columbia, Canada. ^[5] Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. ^[6] Section of Cardiology, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. ^[7] Department of Medicine, University of Mississippi, Jackson, Mississippi, USA. ^[8]

关键词 ACE, angiotensin-converting enzyme ARB, angiotensin receptor blocker ARNI, angiotensin receptor neprilysin inhibitor BB, beta-blocker GDMT, guideline-directed medical therapy HF, heart failure HFrEF, heart failure with reduced ejection fraction MRA, mineralocorticoid receptor agonist SGLT2i, sodium–glucose co-transporter 2 inhibitor T2DM, type 2 diabetes mellitus angiotensin receptor–neprilysin inhibitor beta-blockers eGFR, estimated glomerular filtration rate mineralocorticoid receptor antagonists sodium–glucose co-transporter 2 inhibitors

DOI 10.1016/j.jacbts.2021.10.018

PMID 35663626

发布时间 2022-07-16

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JACC. Basic to translational science

2022年7卷5期

504-517页

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Optimizing Foundational Therapies in Patients With HFrEF: How Do We Translate These Findings Into Clinical Care?

JACC. Basic to translational science

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Optimizing Foundational Therapies in Patients With HFrEF: How Do We Translate These Findings Into Clinical Care?

JACC. Basic to translational science

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JACC. Basic to translational science

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