Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling.

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作者： Tariq,Hamid ^[1] ; Yuanyuan,Xu ^[2] ; Mohamed Ameen,Ismahil ^[2] ; Gregg,Rokosh ^[1] ; Miki,Jinno ^[2] ; Guihua,Zhou ^[1] ; Qiongxin,Wang ^[2] ; Sumanth D,Prabhu ^[2]

作者单位： Division of Cardiology, Washington University School of Medicine, St. Louis, Missouri, USA. ^[1] Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA. ^[2] Birmingham VAMC, Birmingham, Alabama, USA. ^[3]

关键词 CCL, C-C motif chemokine ligand CCR2, C-C chemokine receptor 2 DDR2, discoidin domain receptor 2 DMEM, Dulbecco’s modified Eagle medium EDV, end-diastolic volume EF, ejection fraction ESV, end-systolic volume HF, heart failure IL, interleukin INF, interferon LV, left ventricular Lin, lineage MI, myocardial infarction MSC, mesenchymal stem cell PBS, phosphate-buffered saline PCR, polymerase chain reaction PDGF, platelet-derived growth factor PDGFR, platelet-derived growth factor receptor TGFβ, transforming growth factor beta WGA, wheat germ agglutinin cDNA, complementary DNA cMSC, cardiac mesenchymal stem cell cardiac remodeling fibrosis heart failure mRNA, messenger RNA mesenchymal stem cells myocardial inflammation myofibroblasts platelet-derived growth factor receptor siRNA, small interfering RNA α-SMA, alpha smooth muscle actin

DOI 10.1016/j.jacbts.2022.01.004

PMID 35663630

发布时间 2024-03-21

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JACC. Basic to translational science

2022年7卷5期

465-483页

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Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling.

JACC. Basic to translational science

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JACC. Basic to translational science

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Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling.

JACC. Basic to translational science

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JACC. Basic to translational science

相关期刊

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