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The SARS-CoV-2 spike protein binds and modulates estrogen receptors.

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作者单位: Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, 21224, MD, USA. [1] EXSCALATE, Dompé farmaceutici S.p.A, Napoli, Italy. [2] Center for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA.;Department of Pediatrics, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB-II Room 109, Baltimore, MD, USA.;Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, MD, USA. [3] Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, USA. [4] Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.;Sbarro Institute for Cancer Research and Molecular Medicine, Department of Biology, Temple University, Philadelphia, PA, USA. [5] Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy. [6] Atreius S.a.s., L'Aquila, Italy. [7] Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.;VIMM- Veneto Institute of Molecular Medicine, Fondazione per la Ricerca Biomedica Avanzata, Padova, Italy. [8] Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy. [9] Department for Innovation in Biological, Agro-Food and Forest Systems, DIBAF, University of Tuscia, Viterbo, Italy. [10] Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Rockville, MD, USA. [11] Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. [12] Neuronal Networks Section, National Institute on Drug Abuse Intramural Research Program, Baltimore, 21224, MD, USA. [13] Departament de Patologia i Terapèutica Experimental, Institut de Neurociències, Universitat de Barcelona, L'Hospitalet de Llobregat, Catalonia. [14] Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA. [15] Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA. [16] Dompé farmaceutici S.p.A, L'Aquila, Italy. [17] Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit, National Institute on Drug Abuse Intramural Research Program, Baltimore, 21224, MD, USA.;Department of Psychiatry & Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA. [18]
DOI 10.1101/2022.05.21.492920
PMID 35665018
发布时间 2024-09-23
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