pH sensing controls tissue inflammation by modulating cellular metabolism and endo-lysosomal function of immune cells.
第一作者:
Xiangjun,Chen
第一单位:
Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.;Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA.;Experimental Medicine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
作者:
医学主题词
动物(Animals);结肠炎(Colitis);氢离子浓度(Hydrogen-Ion Concentration);炎症(Inflammation);溶酶体(Lysosomes);小鼠(Mice);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);Th17细胞(Th17 Cells)
DOI
10.1038/s41590-022-01231-0
PMID
35668320
发布时间
2024-09-23
- 浏览5
Nature immunology
1063-1075页
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